Cancer pharmacogenomics: strategies and challenges.

Wheeler H, Maitland M, Dolan M, Cox N, Ratain M. 2016. Nat Rev Genet. PMID: 23183705


The three-dimensional architecture of a bacterial genome and its alteration by genetic perturbation.

Umbarger M, Toro E, Wright M, et al. 2011. Mol Cell. PMID: 22017872


A three-dimensional model of the yeast genome.

Duan Z, Andronescu M, Schutz K, et al. 2010. Nature. PMID: 20436457


Exploring the three-dimensional organization of genomes: interpreting chromatin interaction data.

Dekker J, Marti-Renom M, Mirny L. 2013. Nat Rev Genet. PMID: 23657480


The role of chromosome domains in shaping the functional genome.

Sexton T, Cavalli G. 2015. Cell. PMID: 25768903


Spatial genome organization: contrasting views from chromosome conformation capture and fluorescence in situ hybridization.

Williamson I, Berlivet S, Eskeland R, et al. 2014. Genes Dev. PMID: 25512564


Segmental folding of chromosomes: a basis for structural and regulatory chromosomal neighborhoods?

Nora E, Dekker J, Heard E. 2013. Bioessays. PMID: 23832846


The hierarchy of the 3D genome.

Gibcus J, Dekker J. 2013. Mol Cell. PMID: 23473598


Structure and evolution of transcriptional regulatory networks.

Babu M, Luscombe N, Aravind L, Gerstein M, Teichmann S. 2004. Curr Opin Struct Biol. PMID: 15193307


Structure of the Mediator head module.

Larivière L, Plaschka C, Seizl M, Wenzeck L, Kurth F, Cramer P. 2012. Nature. PMID: 23123849


Transcription of eukaryotic protein-coding genes.

Lee T, Young R. 2000. Annu Rev Genet. PMID: 11092823


Enhancer activation requires trans-recruitment of a mega transcription factor complex.

Liu Z, Merkurjev D, Yang F, et al. 2014. Cell. PMID: 25303530


Architecture of an RNA polymerase II transcription pre-initiation complex.

Murakami K, Elmlund H, Kalisman N, et al. 2013. Science. PMID: 24072820


An atomic model of the interferon-beta enhanceosome.

Panne D, Maniatis T, Harrison S. 2007. Science. PMID: 17574024


A census of human transcription factors: function, expression and evolution.

Vaquerizas J, Kummerfeld S, Teichmann S, Luscombe N. 2009. Nat Rev Genet. PMID: 19274049


Redefining the modular organization of the core Mediator complex.

Wang X, Sun Q, Ding Z, et al. 2014. Cell Res. PMID: 24810298


Cellular senescence: when bad things happen to good cells.

Campisi J, d’Adda di. 2007. Nat Rev Mol Cell Biol. PMID: 17667954


The 3D genome shapes up for pluripotency.

Sexton T, Cavalli G. 2013. Cell Stem Cell. PMID: 23827701


Three-dimensional folding and functional organization principles of the Drosophila genome.

Sexton T, Yaffe E, Kenigsberg E, et al. 2012. Cell. PMID: 22265598


Genome-wide chromatin interactions of the Nanog locus in pluripotency, differentiation, and reprogramming.

Apostolou E, Ferrari F, Walsh R, et al. 2013. Cell Stem Cell. PMID: 23665121


Independence of repressive histone marks and chromatin compaction during senescent heterochromatic layer formation.

Chandra T, Kirschner K, Thuret J, et al. 2012. Mol Cell. PMID: 22795131


Higher order chromatin organization in cancer.

Reddy K, Feinberg A. 2013. Semin Cancer Biol. PMID: 23266653


Role of BMI1, a stem cell factor, in cancer recurrence and chemoresistance: preclinical and clinical evidences.

Siddique H, Saleem M. 2012. Stem Cells. PMID: 22252887


Bmi-1 cooperates with H-Ras to transform human mammary epithelial cells via dysregulation of multiple growth-regulatory pathways.

Datta S, Hoenerhoff M, Bommi P, et al. 2007. Cancer Res. PMID: 17974970


Tumorigenesis: Twist1 links EMT to self-renewal.

Martin A, Cano A. 2010. Nat Cell Biol. PMID: 20885418


BMI1 cooperates with H-RAS to induce an aggressive breast cancer phenotype with brain metastases.

Hoenerhoff M, Chu I, Barkan D, et al. 2009. Oncogene. PMID: 19543317


Life with 6000 genes.

Goffeau A, Barrell B, Bussey H, et al. 1996. Science. PMID: 8849441


Fuzziness and noise in nucleosomal architecture.

Flores O, Deniz Ö, Soler-López M, Orozco M. 2014. Nucleic Acids Res. PMID: 24586063